Elevated Blood Pressure in Adolescent Boys Predicts Endothelial Dysfunction
نویسندگان
چکیده
منابع مشابه
Elevated blood pressure in adolescent boys predicts endothelial dysfunction: the cardiovascular risk in young Finns study.
Hypertension is a major risk factor for atherosclerosis. It may cause or be a consequence of endothelial dysfunction. We studied whether systolic blood pressure measured in childhood and adolescence predicts endothelial-dependent brachial flow-mediated dilation (FMD) in adulthood. Brachial FMD was measured in 2109 white adults, aged 24 to 39 years, in the 21-year follow-up of the Cardiovascular...
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Mas codes for a G protein-coupled receptor that is implicated in angiotensin-(1-7) signaling. We studied the cardiovascular phenotype of Mas-deficient mice backcrossed onto the FVB/N genetic background using telemetry and found that they exhibit higher blood pressures compared with controls. These Mas(-/-) mice also had impaired endothelial function, decreased NO production, and lower endotheli...
متن کاملClinical practice. The child or adolescent with elevated blood pressure.
An audio version of this article is available at NEJM.org A 13-year-old boy visits his pediatrician because his school football team requires medical clearance before the start of the season. On physical examination, his weight is 72 kg (above the 99th percentile for age and sex) and his height is 155 cm (the 50th percentile); his body-mass index (the weight in kilograms divided by the square o...
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An inverse association between birth weight and systolic blood pressure was first noted by Barker et al.1 Since then experimental studies have not only substantiated this finding but also provided insight into the potential mechanisms by which adverse influences during critical periods of fetal life lead to increased blood pressure and cardiovascular risk.2 Recent studies indicate that early po...
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Hypertension is one of the most common chronic medical conditions and to this day has remained one of the important problems of public health. Because of relationship between endothelial dysfunction, atherosclerosis and high blood pressure, returning the endothelium-dependent vasodilatation is known as one of the important goals of treatment for high blood pressure. Drugs should be able to pres...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2006
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000237666.78217.47